IKK (IκB kinase) is an enzyme complex that is the core element of the NF-κB cascade. The complex has two…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/MRT67307-is-a-Dual-Inhibitor-of-the-IKKε-and-TBK-1-2019-07-02.jpg)
IKK {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase} family plays a indispensable role in innate immunity by inducing NF-κB-…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/06/BAY-11-7082-Induces-Apoptosis-in-Myeloma-Cells-Through-Inhibiting-NF-κB-Pathway-2019-06-06.jpg)
NF-κBs are homo- or heterodimers of the structurally related subunits p65 (RelA), RelB, cRel, p50 and p52. NF-κB plays a…