Toll-like receptors (TLRs) are a group of pattern recognition receptors for innate immune cells to detect various pathogen-associated molecular patterns.…
NOD2 (nucleotide-binding oligomerization domain 2) is an intracellular pattern recognition receptor. NOD2 is one of cytoplasmic PRRs, and antigen-presenting cells…
Ionotropic (ligand-gated ion channel), P2X, and metabotropic P2Y receptors belong to P2 receptors. Up to now, eight subtypes of human…
As early as in 1998, the researchers have discovered the selective and non-peptide CXCR2 antagonist SB225002. CXCR1 and CXCR2 are…