IL-8 Archives - Immune System Research

GSK717 is a Selective NOD2 (Nucleotide-Binding Oligomerization Domain 2) Inhibitor

2020-07-30 Edward Jenner

NOD2 (nucleotide-binding oligomerization domain 2) is an intracellular pattern recognition receptor. NOD2 is one of cytoplasmic PRRs, and antigen-presenting cells and certain mucosal epithelia primarily express it. It assembles with…

NF546 is a Selective Non-Nucleotide P2Y11 Agonist

2020-02-02 Edward Jenner

Ionotropic (ligand-gated ion channel), P2X, and metabotropic P2Y receptors belong to P2 receptors. Up to now, eight subtypes of human P2Y receptors are P2Y1, P2Y2, P2Y4, P2Y6, and P2Y11-14. P2…

SB225002 is a Selective CXCR2 Antagonist

2019-08-08 Edward Jenner

As early as in 1998, the researchers have discovered the selective and non-peptide CXCR2 antagonist SB225002. CXCR1 and CXCR2 are two chemokine receptors in Neutrophils. They play an important role…

Immune System Research

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