![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/09/TAK-676.jpg)
Stimulator of interferon genes (STING), an integral ER-membrane protein, is a protein that in humans is encoded by the STING1…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/09/C-178-is-a-Covalent-Small-Molecule-Inhibitor-of-STING-2019-09-26.jpg)
In the previous blog, I have introduced C-176 as a strong and covalent mouse STING inhibitor. Today, I’d like to…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/PS372424-is-a-Specific-Agonist-for-The-Human-CXCR3-2019-07-11.jpg)
Chemokines are low-molecular weight proteins that mediate the migration of leucocytes. Crucially, chemokines exert their effects by binding to specific…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/MRT67307-is-a-Dual-Inhibitor-of-the-IKKε-and-TBK-1-2019-07-02.jpg)
IKK {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase} family plays a indispensable role in innate immunity by inducing NF-κB-…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/06/NG25-a-Dual-Inhibitor-of-TAK1-and-MAP4K2-Suppresses-Production-of-IFNα-2019-06-24.jpg)
TAK1 is also called Mitogen-activated protein kinase kinase kinase 7 (MAP3K7). It belongs to the serine/threonine protein kinase family. The…