In the previous blog, I have introduced C-176 as a strong and covalent mouse STING inhibitor. Today, I’d like to…
Chemokines are low-molecular weight proteins that mediate the migration of leucocytes. Crucially, chemokines exert their effects by binding to specific…
IKK {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase} family plays a indispensable role in innate immunity by inducing NF-κB-…
TAK1 is also called Mitogen-activated protein kinase kinase kinase 7 (MAP3K7). It belongs to the serine/threonine protein kinase family. The…
The abnormal activation of innate immune pathways partispate in the progress of various diseases. Unfortunately, the development of drugs specifically…