![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/04/Deucravacitinib-is-an-Orally-Active-TYK2-Allosteric-Inhibitor-for-Autoimmune-Diseases-Research-2023-0411.jpg)
Tyrosine kinase 2 (TYK2) is a member of the JAK kinase family. Besides, it regulates signal transduction downstream of the…
Stimulator of interferon genes (STING), an integral ER-membrane protein, is a protein that in humans is encoded by the STING1…
In the previous blog, I have introduced C-176 as a strong and covalent mouse STING inhibitor. Today, I’d like to…
Chemokines are low-molecular weight proteins that mediate the migration of leucocytes. Crucially, chemokines exert their effects by binding to specific…
IKK {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase} family plays a indispensable role in innate immunity by inducing NF-κB-…