![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/PRN694-is-a-Dual-Inhibitor-of-ITK-and-RLK-2019-07-30.jpg)
Interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK or TXK) are essential mediators of intracellular signaling in both normal…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/BMS-509744-is-a-Selective-and-ATP-Competitive-ITK-Inhibitor-2019-07-09.jpg)
In general, proper immune responses depend on T-cell activation during antigen presentation. However, relaxation of t-cell stimulation often leads to…