![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/NMS-E973-is-a-Selective-and-BBB-Penetrated-HSP90-Inhibitor-2020-11-17.jpg)
Hsp90 is a molecular chaperone, it is essential for the conformational stability and activity of many key oncogenic proteins. These…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/BMS-906024-is-an-Orally-Active-γ-Secretase-and-Notch-Inhibitor-2020-09-23.jpg)
Gamma secretase (γ-Secretase) is a kind of multi-subunit protease complex, which is an indispensable membrane protein. Specifically, γ-Secretase cleaves one-way…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/06/MI-3454-is-an-Orally-Active-Menin-MLL1-Interaction-Inhibitor-2020-06-24.jpg)
The protein-protein interaction between menin and MLL fusion proteins plays a critical role in the pathogenesis of MLL leukemia. The…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/A-205804-is-a-Selective-Inhibitor-of-E-selectin-and-ICAM-1-2020-04-30.jpg)
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. The presence of integrins allows rapid and flexible responses to…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/02/TEI-9647-a-Vitamin-D-antagonist-Inhibits-Osteoclast-Formation-2020-03-05.jpg)
The vitamin D receptor (VDR) is a member of the nuclear receptor family of transcription factors. 1α,25(OH)2D3 is to mediate biological…