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Tag: LMP

ML604440 is a Specific Proteasome β1i (LMP2) Subunit Inhibitor

2019-09-15 Edward Jenner

The ubiquitin-proteasome system exerts numerous essential regulatory functions in almost all cell biological pathways. The 26S proteasome degrades polyubiquitylated protein…

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Posted in: Autoimmune Disorders, Colitis Filed under: EAE, LMP, MHC, Proteasome

KZR-504 is a Highly Selective Inhibitor of Immunoproteasome Low Molecular Mass Polypeptide 2

2019-05-21 Edward Jenner

A study from Henry W. B. Johnson discovered and described KZR-504 as a highly selective inhibitor of immunoproteasome low molecular…

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Posted in: Autoimmune Disorders Filed under: LMP, Proteasome
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