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Tag: LpxC

ACHN-975 is a First-in-class and Selective LpxC Inhibitor

2019-10-21 Edward Jenner

The bacterial enzyme UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase (LpxC) catalyzes the first committed step of lipid A biosynthesis. Additionally, the process represents a…

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Posted in: Bacterial Filed under: Gram-negative, LpxC
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