AZD9898 is an Orally Active LTC4S Inhibitor for Asthma Treatment
The arachidonic acid cascade forms a plethora of proinflammatory and pro-resolution lipid metabolites, including prostaglandins, thromboxanes, and leukotrienes. In particular, the cysteinyl leukotrienes (cysLTs) play an important role in asthma….