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Tag: Lymphoma

AQX-435 is a Potent SHIP1 Activator and an Apoptosis Inducer

2020-10-28 Edward Jenner

PI3Ks are key drivers of the survival and growth of normal B cells. PI3K catalyzes the phosphorylation of PI(4,5)P2 to…

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Posted in: Cancer Immunology Filed under: Apoptosis, Lymphoma, PI3K, SHIP1

TAS05567 is a Highly Selective, ATP-competitive and Orally Active Syk Inhibitor

2020-03-14 Edward Jenner

Autoimmune diseases, including rheumatoid arthritis (RA) and immune thrombocytopenia (ITP), are caused by aberrant immune responses. ITP is an autoimmune…

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Posted in: Autoimmune Disorders Filed under: FLT3, JAK2, Lymphoma, RET, SYK

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