Macrophage Archives - Immune System Research

ADH-503 is an Orally Active and Allosteric CD11b Agonist

2020-02-13 Edward Jenner

Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant myeloid cell infiltrates. The immunosuppression, fibrosis, T cell dysfunction, and poor prognosis in patients with PDAC associate with these infiltrates. The cells…

Ly93, an Oral Active SMS2 Inhibitor, Has Anti-Atherosclerotic Activity

2019-06-23 Edward Jenner

The sphingomyelin synthase 2 (SMS2) is a potential target for pharmacological intervention in atherosclerosis. However, as far as now, reports about selective SMS2 inhibitors and their pharmacological activities were lacked….

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Tag: Macrophage

ADH-503 is an Orally Active and Allosteric CD11b Agonist

2020-02-13 Edward Jenner

Ly93, an Oral Active SMS2 Inhibitor, Has Anti-Atherosclerotic Activity

2019-06-23 Edward Jenner