5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. Type: 5-HT1, 5-HT2, 5-HT3, 5-HT4,…
The kinase is an enzyme. And it catalyzes the transfer of a phosphate group from a high-energy donor molecule to a specific target molecule. This process is phosphorylation. In general,…
Adrenergic receptors (also known as adrenoceptors, ARs) belong to the guanine nucleotide-binding G protein-coupled receptor (GPCR) superfamily. And Adrenergic receptors are membrane receptors that activate heterotrimeric G proteins following the…
Retinoblastoma protein (Rb), a tumor suppressor protein, is dysfunctional in several major cancers. Specifically, one of the functions of Rb is to prevent excessive cell growth by inhibiting cell cycle…
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. Firstly, in B16-F10 melanoma cells, 3M-011 treatment can decrease B16-F10 melanoma cell counts as a dose-dependent manner. 3M-011 potentiates…