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Tag: mGlu5

VU0409106 is a Potent and Selective mGlu5 NAM With Anxiolytic Effects

2022-08-23 Edward Jenner

mGluR (metabotropic glutamate receptor) is a type of glutamate receptor that are active through an indirect metabotropic process. They are…

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Posted in: Neurological Disease Filed under: Anxiolytic, Brain-penetrant, mGlu5

HTL14242 is an Orally Active mGlu5 NAM

2021-03-23 Edward Jenner

Metabotropic glutamate receptor 5 (mGlu5) is an excitatory GQ coupled G protein-coupled receptor, which is mainly expressed in the postsynaptic…

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Posted in: Neurological Disease Filed under: mGlu5, NAM
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