DPTIP is a Brain Penetrant N-SMase 2 and Exosome Inhibitor
Neutral sphingomyelinase 2 (nSMase2) catalyzes the formation and release of extracellular vesicles (EVs) . Human nSMase2 catalyzes the hydrolysis of sphingomyelin to phosphorylcholine and ceramide. DPTIP, a potent brain penetrant…