EB-47, a NAD+ Mimetic, is a Potent and Selective PARP-1/ARTD-1 Inhibitor
Poly-ADP-ribose polymerases (PARPs) involves regulating important cellular processes, such as DNA repair, aging, and apoptosis, among others. Human cancer cells carrying BRCA1 and BRCA2 mutations are sensitive to human PARP-1…