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Tag: P2X3

PPADS is a Non-Selective P2X Receptor Antagonist

2022-01-11 Edward Jenner

P2X receptors are a family of seven (P2X1R-P2X7R) cation permeable ligand-gated ion channels (LGICs) that open in response to binding…

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Posted in: Neurological Disease Filed under: NCXREV, P2X, P2X1, P2X2, P2X3, P2X5

BLU-5937 is a Potent, Selective and Orally Active P2X3 Homotrimeric Receptor Antagonist

2020-04-29 Edward Jenner

Cough is an essential defensive mechanism for the airways to prevent harmful gasses or particles from the environment. The chronic…

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Posted in: Respiratory Infection Filed under: Anti-tussive, P2X3
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