PG - Immune System Research

Fuzapladib (IS-741) is A Potent Phospholipase A2 Inhibitor

Edward Jenner 2023-02-16

Phospholipase is a member of a very complex group of enzymes that break down phospholipids into fatty acids and other compounds. Phospholipase is defined by the enzymatic reaction they catalyze.…

Inflammation

DuP-697 is a Selective and Orally Active COX-2 Inhibitor

Edward Jenner 2020-03-26

COX-2 is the more important source of prostanoid formation in inflammation and in proliferative diseases. In particular, COX-2 prefers prostaglandin I synthase and the microsomal PGES isozymes. DuP-697 is an…