![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/IHMT-PI3Kδ-372-is-a-Potent-and-Selective-PI3Kδ-Inhibitor-2020-01-06.jpg)
PI3Kδ belongs to the class I Phosphoinositide 3-kinases (PI3Ks). PI3Kδ plays a critical role in chronic obstructive pulmonary disease (COPD).…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/MSC2360844-is-an-Orally-Active-and-Selective-PI3Kδ-Inhibitor-2020-11-07-1.jpg)
SLE is a complex autoimmune inflammatory disease that affects multiple organs with unpredictable flares. Autoantibody/antigen immune-complexes in turn can activate…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/10/AQX-435-is-a-Potent-SHIP1-Activator-and-an-Apoptosis-Inducer-2020-10-28.jpg)
PI3Ks are key drivers of the survival and growth of normal B cells. PI3K catalyzes the phosphorylation of PI(4,5)P2 to…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/GS-9901-an-Orally-Active-PI3Kδ-Inhibitor-Has-Potential-to-Treat-Rheumatoid-Arthritis-2019-07-24.jpg)
Phosphoinositide 3-kinase (PI3K) plays an indispensable role in the signal transduction of numerous cellular functions via the formation of the…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/LAS191954-is-an-Orally-Active-PI3Kδ-Inhibitor-2019-07-23.jpg)
The phosphatidylinositol-3-kinase (PI3K) signal transduction pathway plays an indispensable role in different cellular processes involving metabolism, proliferation, differentiation or activation.…