![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/12/ACT001-is-an-Orally-Active-PAI-1-Inhibitor-2021-12-16.jpg)
Glioblastoma (GBM) is the most common and most aggressive primary malignant brain tumour in adults, with a high morbidity, high…
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PI3Kδ belongs to the class I Phosphoinositide 3-kinases (PI3Ks). PI3Kδ plays a critical role in chronic obstructive pulmonary disease (COPD).…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/MSC2360844-is-an-Orally-Active-and-Selective-PI3Kδ-Inhibitor-2020-11-07-1.jpg)
SLE is a complex autoimmune inflammatory disease that affects multiple organs with unpredictable flares. Autoantibody/antigen immune-complexes in turn can activate…
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PI3Ks are key drivers of the survival and growth of normal B cells. PI3K catalyzes the phosphorylation of PI(4,5)P2 to…
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Phosphoinositide 3-kinase (PI3K) plays an indispensable role in the signal transduction of numerous cellular functions via the formation of the…