Calyculin A is a PP1 and PP2A Inhibitor
A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphatases (PPs) are the primary effectors of…
A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphatases (PPs) are the primary effectors of…
Mitosis is an attractive target for selective anticancer treatment. Mitotic kinases, including CDKs, AURKs, and PLK1, associate with tumor progression and prognosis. However, these agents are cytotoxicity to healthy cells. inhibitors against…