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Tag: Prostaglandin

CAY10471 is a Selective and Orally Active CRTH2 Antagonist

2020-05-07 Edward Jenner

CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. In PC12 cells, CAY10471 blocks 15d-PGJ2-induced…

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Posted in: Allergy, Asthma, Fibrosis, Kidney Fibrosis, Rhinitis Filed under: CHS, CRTH2, Prostaglandin

DuP-697 is a Selective and Orally Active COX-2 Inhibitor

2020-03-26 Edward Jenner

COX-2 is the more important source of prostanoid formation in inflammation and in proliferative diseases. In particular, COX-2 prefers prostaglandin…

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Posted in: Inflammation Filed under: Anti-Inflammatory, Anti-Tumor, COX, PG, Prostaglandin

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