NADPH oxidases (NOX), catalyzing the reduction of molecular oxygen to form the superoxide radical anion (O₂⁻) and hydrogen peroxide (H₂O₂).…
Sphingosine-1-phosphate (S1P) is a ligand for G-protein-coupled receptors, it is responsible for some cell-intrinsic and extrinsic activities. RPC1063 is a…
Prolyl hydroxylases (PHDs) target hypoxia-inducible factor-1α (HIF-1α) for degradation. Hypoxia inactivates PHDs, causing accumulation of HIF-1α. In turn, HIF-1 further…