R 59-022 is a Diacylglycerol Kinase Inhibitor and a 5-HTR Antagonist
Diacylglycerol kinases are lipid kinases that phosphorylate DAG to generate phosphatidic acid (PA). In mammals, there are ten isoforms of DGKs. R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM)….