K-975 is an Orally Active and Selective TEAD Inhibitor
The transcriptional enhanced associate domain (TEAD) is a transcription factor. In mammals, TEAD has four different isoforms namely TEAD1 (TEF-1/NTEF), TEAD2 (TEF-4/ETF), TEAD3 (TEF-5/ETFR-1), and TEAD4 (TEF-3/ETFR-2/FR-19). And there is…