Orexin A is a Specific Agonist for G-Protein-Coupled Receptor OX1R
The orexin receptors are G-protein-coupled receptors (GPCRs), and consist of orexin receptor 1 (OX1R) and orexin receptor 2 (OX2R) subtypes. OX1R binds orexin-A with high affinity, but it has considerably…