5-LOX - Immune System Research

Diflapolin is a Highly Active dual FLAP and sEH Inhibitor

The arachidonic acid (AA) cascade plays a central role in the biosynthesis of lipid mediators (LMs) with anti-inflammatory properties cascade plays an important role in the biosynthesis of lipid mediators…

Inflammation

PF-4191834 is an Orally Active Inhibitor of the 5-Lipoxygenase

Edward Jenner 2019-08-03

The 5-lipoxygenase (LOX) pathway plays an important role in the pathophysiology of asthma. 5-LOX is an important arachidonic acid-metabolizing enzyme producing leukotrienes and other proinflammatory lipid mediators. Moreover, it has…

Diflapolin is a Highly Active dual FLAP and sEH Inhibitor

PF-4191834 is an Orally Active Inhibitor of the 5-Lipoxygenase

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