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Tag: 5-LOX

Diflapolin is a Highly Active dual FLAP and sEH Inhibitor

2021-01-26 Edward Jenner

The arachidonic acid (AA) cascade plays a central role in the biosynthesis of lipid mediators (LMs) with anti-inflammatory properties cascade…

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Posted in: Peritonitis Filed under: 5-LOX, FLAP, Peritonitis, sEH

PF-4191834 is an Orally Active Inhibitor of the 5-Lipoxygenase

2019-08-03 Edward Jenner

The 5-lipoxygenase (LOX) pathway plays an important role in the pathophysiology of asthma. 5-LOX is an important arachidonic acid-metabolizing enzyme…

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Posted in: Inflammation Filed under: 5-LOX, Anti-Inflammatory
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