The proteasome is part of the main mechanism by which cells regulate specific protein concentration and degrade misfolded proteins. Specifically,…
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME). Cell surface receptors and their ligands can be internalized…
Some Gram-negative pathogens have accumulated enough resistance mechanisms to render them virtually untreatable by modern antibacterial chemotherapy. A mainstay for…
Cancer initiation and progression are mediated through dysregulation of multiple signaling pathways. Specificity protein 1 (Sp1) is a zinc-finger transcription…
Antibiotics, also known as antibacterials, are medications that destroy or slow down the growth of bacteria. Since ancient times, many…