![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/SBP-7455-is-an-Orally-Active-Dual-ULK1-ULK2-Autophagy-Inhibitor-2020-01-23.jpg)
Autophagy is a multi-step pathway initiated through the ULK preinitiation complex, which consists of unc-51-like autophagy activating kinase 1 (ULK1)…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/GW406108X-is-a-Potent-Autophagy-ULK1-and-Specific-Kif15-Kinesin-12-Inhibitor-2020-12-02.jpg)
ULK1/2 is an important protein in autophagy for mammalian cells and homologous Atg1 in yeast. Specifically, it is part of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/RSVA405-is-a-Potent-and-Orally-Active-AMPK-Activator-2020-11-21.jpg)
AMP-activated protein kinase (AMPK) is a central regulator of cellular and whole-body energy homeostasis. AMPK regulates cellular energy levels by…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/PF-543-is-a-Selective-and-Reversible-SPHK1-Inhibitor-2020-10-06.jpg)
S1P (sphingosine 1-phosphate) is an extracellular ligand at five cognate GPCRs and a consequential intracellular lipid intermediate. It affects diverse…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/05/BRD5631-Enhances-Autophagy-through-mTOR-Independent-Pathway-2019-05-14.jpg)
Scientists have demonstrated the regulation of autophagy in inflammation, neurodegeneration, infection, and autoimmunity. And the findings motivate the use of…