TAK-779 is an Antagonist of CCR5 and CXCR3, with Anti-HIV-1 Effect
Nowadays, people are no strangers to AIDS. It is a kind of infectious disease caused by HIV. The latter primarily acts on human immune system, like CD4+ T cells. These…
Nowadays, people are no strangers to AIDS. It is a kind of infectious disease caused by HIV. The latter primarily acts on human immune system, like CD4+ T cells. These…
Renal ischemia/reperfusion injury (IR) is a major clinical problem found in shock, renal transplantation and other clinical settings. Neutrophils and macrophages rapidly infiltrate the kidney after renal ischemia-reperfusion injury. Chemokines…
Monocyte chemoattracant-1 (MCP-1) stimulates leukocyte chemotaxis to inflammatory sites, such as rheumatoid arthritis, atherosclerosis, and asthma, by use of the MCP-1 receptor, CCR2. CCR2 is also a member of the…
The prevalence of asthma and the associated cost burden for the health care system is high. The chemokine receptor Chemokine (C-C motif) receptor 8 (CCR8) is associated with asthma. A…