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Tag: CD11b

Leukadherin-1 is a Specific Agonist of the Leukocyte Surface αMβ2 Integrin CD11b/CD18

2020-11-05 Edward Jenner

In molecular biology, CD18 (integrin beta chain 2) is an integrin beta chain protein encoded by the human itgb2 gene.…

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Posted in: Inflammation, Lung Inflammation Filed under: CD11b, CD18, CR3, Integrin, αMβ2

ADH-503 is an Orally Active and Allosteric CD11b Agonist

2020-02-13 Edward Jenner

Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant myeloid cell infiltrates. The immunosuppression, fibrosis, T cell dysfunction, and poor prognosis…

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Posted in: Cancer Immunology, Inflammation Filed under: Anti-Tumor, CD11b, CD18, Macrophage

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