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Tag: CD4

GSK046 is a Selective and Orally Active BET Inhibitor

2020-08-01 Edward Jenner

The BET (bromodomain and extraterminal domain) family includes BRDT, BRD2, BRD3, and BRD4 epigenetic reader proteins. They contain N-terminal tandem…

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Posted in: Immunology Filed under: BET, BRD4 BD2, CD4, KLH

The Potent CXCR4 Antagonist KRH-3955 is an Orally Bioavailable Inhibitor of HIV-1

2020-07-18 Edward Jenner

CXCR-4 is an α-chemokine receptor specific for SDF-1, which is a molecule with the strong chemotactic activity of lymphocytes. Specifically,…

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Posted in: HIV, Viral Immunology Filed under: CD4, CXCR4, HIV-1, SDF-1α

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