VPC 23019 is a Competitive Antagonist of S1P1 and S1P3 Receptors and an Agonist of S1P4 and S1P5 Receptors.
Sphingosine 1-phosphate (S1P) is a lysophospholipid mediator. S1P evokes a variety of cellular responses by stimulation of five members of the endothelial cell differentiation gene receptor family. The recent development…