![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/11/Brequinar-DUP785-is-a-Potent-DHODH-Inhibitor-2021-11-06.jpg)
Dihydroorotate dehydrogenase (DHODH), located in the inner membrane of mitochondria, is an iron-containing flavin-dependent enzyme. Using the cofactor ubiquinone, DHODH…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/06/DSM705-is-a-Plasmodium-DHODH-Inhibitor-2021-06-30.jpg)
Malaria is one of the most widespread and ancient infectious diseases of humanity. In particular, Dihydroorotate dehydrogenase (DHODH) acts as…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/06/BRD9185-is-a-DHODH-Inhibitor-with-Antimalarial-Activity-2019-06-13.jpg)
In our previous blogs, we have introduced two compounds that have antimalarial activity, BDA-410 and UCT943. BDA-410 is a calpain…