ER Stress Archives - Immune System Research

ZX-29, a Selective ALK Inhibitor, Induces Apoptosis via ER Stress

2020-04-16 Edward Jenner

Anaplastic lymphoma kinase (ALK) is a member of the insulin receptor superfamily. Specifically, the fusion form can activate ALK, and ALK is continuously activated. Besides, the abnormal activation of ALK abnormally…

KIRA-7 is an Allosteric IRE1α Kinase/Rnase Inhibitor

2020-02-25 Edward Jenner

Idiopathic pulmonary fibrosis (IPF) is a disease of progressive fibrosis and respiratory failure. Endoplasmic reticulum stress (ER stress) implicates in the pathogenesis of idiopathic pulmonary fibrosis. ER stress activates a…

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ZX-29, a Selective ALK Inhibitor, Induces Apoptosis via ER Stress

2020-04-16 Edward Jenner

KIRA-7 is an Allosteric IRE1α Kinase/Rnase Inhibitor

2020-02-25 Edward Jenner