![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/GSK-J4-is-a-Dual-Inhibitor-of-H3K27me3-me2-Demethylases-JMJD3-KDM6B-and-UTX-KDM6A-2021-02-18.jpg)
H3K27me3 is an epigenetic modification of DNA packaging protein histone H3. Specifically, it is a marker for the trimethylation of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/PACMA-31-is-an-Irreversible-and-Orally-Active-Protein-Disulfide-Isomerase-PDI-Inhibitor.jpg)
Ovarian cancer is one of the leading causes of death in women with gynecological cancers in the United States. About…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/10/MK-28-is-a-Potent-and-Selective-PERK-Activator-2020-10-15.jpg)
Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is an endoplasmic reticulum-associated stress sensor protein. PERK phosphorylates eukaryotic initiation factor…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/ZX-29-a-Selective-ALK-Inhibitor-Induces-Apoptosis-via-ER-Stress-2020-04-16.jpg)
Anaplastic lymphoma kinase (ALK) is a member of the insulin receptor superfamily. Specifically, the fusion form can activate ALK, and ALK…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/02/KIRA-7-is-an-Allosteric-IRE1α-Kinase-Rnase-Inhibitor-2020-02-25.jpg)
Idiopathic pulmonary fibrosis (IPF) is a disease of progressive fibrosis and respiratory failure. Endoplasmic reticulum stress (ER stress) implicates in…