![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/Cobicistat-is-a-Selective-CYP3A-Inhibitor-and-a-Pharmacokinetic-Enhancer-of-HIV-Inhibitors-2020-12-22.jpg)
The highly active antiretroviral therapy (HAART) can transform the human immunodeficiency virus (HIV) infection into a manageable chronic disease in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/BRD3308-a-Highly-Selective-HDAC3-Inhibitor-Activates-HIV-1-Transcription-and-Disrupts-HIV-1-Latency-2020-05-02.jpg){kind=spacer}
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl-lysine amino acid on a histone.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/03/PF-3450074-is-a-HIV-1-Capsid-Protein-Inhibitor-2020-03-24.jpg)
Human immunodeficiency virus type 1 (HIV-1) infection leads to depletion of the immune dysfunction. Thereby results in immunodeficiency and vulnerability…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/03/ZL0580-a-Selective-BD1-BRD4-Inhibitor-Induces-HIV-Epigenetic-Suppression-2020-03-12.jpg)
HIV integrates its provirus into the host genome and establishes latent infection. Antiretroviral therapy (ART) can effectively suppress active HIV…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/01/MS417-is-a-BET-Specific-BRD4-Inhibitor-2020-01-17.jpg)
NF-κB-mediated inflammation is a major pathology in kidney diseases, such as non-kidney inflammatory diseases, and rheumatoid arthritis. HIV infection in…