TLR9 is an important receptor existing in immune system cells (including dendritic cells, macrophages, and other antigen-presenting cells). TLR9 recognizes…
HIV is a lentivirus (a subgroup of retrovirus) that causes the acquired immunodeficiency syndrome (AIDS). HIV infects vital cells in…
Aplaviroc (AK 602), an SDP derivative, is a potent CCR5 antagonist. Additionally, the IC50s are 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and…
Protein kinase C (PKC) is a family of protein kinase enzymes with 15 isoforms that can regulate the protein function.…
The highly active antiretroviral therapy (HAART) can transform the human immunodeficiency virus (HIV) infection into a manageable chronic disease in…