![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/02/IBS008738-is-a-Potent-TAZ-Activator-2022-02-17-02-1600x914.jpg)
The transcriptional coactivator with a PDZ-binding motif (TAZ, also called WWTR1) acts as an N-terminal TEAD-binding domain, one or two…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/BRD6989-Inhibits-CDK8-and-Upregulates-IL-10-2020-11-19.jpg)
Interleukin 10 (IL-10) is an anti-inflammatory cytokine. Specifically, IL-10 is a cytokine with multiple effects in immune regulation and inflammation.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/BRD6989-Inhibits-CDK8-and-Enhances-IL-10-Production-2019-12-24.jpg)
The cytokine IL-10 promotes immune homeostasis via multiple mechanisms. It includes suppressing inflammatory cytokine production by innate immune cells and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/11/SEW2871-is-a-Highly-Selective-and-Orally-Active-S1P1-Agonist-2019-11-07.jpg)
G protein-coupled receptors (GPCRs) are also known as 7TM receptors due to their transmembrane domains. they constitute the largest superfamily…