![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/09/Tofacitinib-is-an-Orally-Active-JAK-Inhibitor-2021-09-24.jpg)
The Janus kinase (JAK) family of protein-tyrosine kinase has four members: JAK1, JAK2, JAK3, and TYK2. The Janus kinases share…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/07/BD750-an-Effective-Immunosuppressant-is-a-JAK3-STAT5-Inhibitor-2020-07-28.jpg)
Interleukin-2 (IL-2) is a pleiotropic cytokine and controls the differentiation and homeostasis of both pro- and anti-inflammatory T cells. The…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/02/SP4206-is-an-IL-2-IL-2Rα-Interaction-Inhibitor-2020-02-22.jpg)
Protein–protein interactions are major regulators of cell biology and important targets in drug discovery. Specifically, protein-protein interactions are driven by…