![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/Ac-FLTD-CMK-a-GSDMD-Derived-Inhibitor-is-a-Caspase-Inhibitor-2020-12-05.jpg)
Caspase is a family of protease that plays an important role in programmed cell death. Specifically, caspase also has other…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/JC-171-is-a-Selective-NLRP3-Inflammasome-Inhibitor-2020-08-05.jpg)
Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease of the central nervous system (CNS) and is a leading cause of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/11/YQ128-is-a-Selective-and-Second-Generation-NLRP3-Inflammasome-Inhibitor-2019-11-20.jpg)
In the NLR family, the NLRP3 inflammasome plays essential roles in the maturation and production of IL-1β and IL-18. Dysregulation…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/10/CY-09-is-a-Selective-and-Direct-NLRP3-Inhibitor-for-Inflammatory-Disorders-Treatment-2019-10-23.jpg)
The inflammasomes are protein complexes. The innate immune sensors, including NOD-like receptor (NLR) family members (NLRP1, NLRP3, and NLRC4) as…