![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/06/BMS-587101-is-an-Orally-Active-Antagonist-of-LFA-1-2021-06-12.jpg)
Leukocyte function-associated antigen-1 (LFA-1), also known as CD11a/CD18 and αLβ2, is a member of the β2-integrin family found on lymphocytes…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/06/OATD-01-is-an-Orally-Active-and-Selective-Chitinase-Inhibitor-2021-06-10.jpg)
Chitinases are chitin-degrading enzymes that belong to the glycosyl hydrolase family. It includes enzymatically active chitinases and chitinase-like proteins without…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/03/CC-90001-is-a-selective-and-Orally-Active-Inhibitor-of-JNK-2021-03-10.jpg)
c-Jun N-terminal kinases (JNKs) belong to the mitogen-activated protein kinase family and are responsive to stress stimuli. Specifically, JNKs belong…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/02/KIRA-7-is-an-Allosteric-IRE1α-Kinase-Rnase-Inhibitor-2020-02-25.jpg)
Idiopathic pulmonary fibrosis (IPF) is a disease of progressive fibrosis and respiratory failure. Endoplasmic reticulum stress (ER stress) implicates in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/09/BMS-986020-is-a-High-affinity-LPA1-Antagonist-for-Idiopathic-Pulmonary-Fibrosis-2019-09-18.jpg)
Idiopathic pulmonary fibrosis is an interstitial lung disease. Idiopathic pulmonary fibrosis commonly results in respiratory failure and death. Unfortunately, Idiopathic…