MAGL - Immune System Research

JZP-361 is a Potent and Reversible MAGL Inhibitor

Edward Jenner 2022-07-25

Monoacylglycerol lipase (MAGL) is a 33 kDa membrane-related member of serine hydrolase superfamily. Besides, it contains the classical GXSXG common sequence common to most serine hydrolases. MAG is the main…

Fibrosis

MJN110 is an Orally Active and Selective Monoacylglycerol Lipase Inhibitor

Edward Jenner 2019-10-16

The serine hydrolases monoacylglycerol lipase (MAGL) is responsible for degrading 2-arachidonoyl glycerol (2-AG). And the fatty acid amide hydrolase (FAAH) degrades N-arachidonoyl ethanolamine (anandamide or AEA). They are endogenous agonists…

JZP-361 is a Potent and Reversible MAGL Inhibitor

MJN110 is an Orally Active and Selective Monoacylglycerol Lipase Inhibitor

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