Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is a bioactive lipid mediator, found in body fluids and tissues. S1P regulates lymphocyte recirculation, cardiac function and a…
Sphingosine 1-phosphate (S1P) is a bioactive lipid molecule secreted into the circulation mainly by erythrocytes and endothelial cells. First of all, S1P acts via G protein-coupled S1P receptors (S1PRs), is…
Multiple sclerosis is a demyelinating disease with damaged insulating covers of nerve cells in the brain and spinal cord. It is a kind of inflammatory disease, affects the central nervous…
Multiple sclerosis is a potentially disabling disease of the brain and spinal cord in central nervous system. Multiple sclerosis is an autoimmune disorder; autoimmune disorders occur when the immune system…
Sphingosine-1-phosphate (S1P) is a biologically active sphingolipid. It functions via the five G protein-coupled receptors (S1P1-S1P5). S1P1 plays a major role in regulating lymphocyte trafficking, exerting its immunomodulatory effect. A…