Oxidative stress describes an imbalance between reactive oxygen species (ROS) synthesis and antioxidants. Normally, cells possess antioxidant defense systems that include ROS degrading molecules (ROS scavengers), such as uric acid,…
NOX1 and NOX4 are two members of the NADPH oxidase family, as well as multiple transmembrane proteins on the cell membrane. NOX1/4 catalyzes oxygen and NADPH into superoxide radicals to participate…
NADPH oxidases (NOX), catalyzing the reduction of molecular oxygen to form the superoxide radical anion (O₂⁻) and hydrogen peroxide (H₂O₂). NOX involves in several pathological conditions, such as stroke, diabetes,…