SR-BI is the HDL1 receptor and plays a key role in lipoprotein metabolism. In mice, SR-BI distributes in hepatocytes, it controls plasma lipoprotein metabolism. Besides, in steroidogenic cells, SR-BI enables…
Diacylglycerol kinases are lipid kinases that phosphorylate DAG to generate phosphatidic acid (PA). In mammals, there are ten isoforms of DGKs. R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM)….
Neutrophils are recruited into inflammatory areas to eliminate invasive pathogens in inflammatory process. Unfortunately, excessive recruitment and activation of neutrophils are harmful to human health. Moreover, that situation is involved…