In our cancer blog, we have introduced a large number of PROTACs. A1874 exhibits a nultin-based BRD4-degrading PROTAC. MT-802 shows…
In previous blogs, we have introduced a lot of PROTAC based degraders, including TD-428, HJB97, A1874, etc. Coincidentally most of…
Glioblastomas (also called GBM) are malignant Grade IV tumors, where a large portion of tumor cells are reproducing and dividing at…
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase. ALK belongs to the insulin receptor kinase subfamily. Nucleophosmin (NPM)-ALK is…