ARD-266 is a Highly Potent AR PROTAC Degrader
In our cancer blog, we have introduced a large number of PROTACs. A1874 exhibits a nultin-based BRD4-degrading PROTAC. MT-802 shows as a PROTAC degrader of BTK for C481S mutant CLL…
In our cancer blog, we have introduced a large number of PROTACs. A1874 exhibits a nultin-based BRD4-degrading PROTAC. MT-802 shows as a PROTAC degrader of BTK for C481S mutant CLL…
In previous blogs, we have introduced a lot of PROTAC based degraders, including TD-428, HJB97, A1874, etc. Coincidentally most of them are all PROTAC-based BET degraders. Today, I’d like to…
Glioblastomas (also called GBM) are malignant Grade IV tumors, where a large portion of tumor cells are reproducing and dividing at any given time. They are nourished by an ample and…
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase. ALK belongs to the insulin receptor kinase subfamily. Nucleophosmin (NPM)-ALK is a fusion protein. NPM-ALK fusion protein expresses in the majority…