G protein-coupled receptors (GPCRs) are also known as 7TM receptors due to their transmembrane domains. they constitute the largest superfamily…
Sphingosine 1-phosphate (S1P) is a lysophospholipid mediator. S1P evokes a variety of cellular responses by stimulation of five members of…
Immunosuppressants that prevents acute rejection has dramatically improved graft survival in organ transplantation. For instance, calcineurin inhibitors (CNIs) improve the…