Voxelotor is an HbS Inhibitor for Sickle Cell Disease (SCD) Research
Sickle cell hemoglobin (HbS) is caused by a mutation that replaces a glutamic acid at residue 6 in beta-globin with a valine. This amino acid substitution results in the formation…
Voxelotor (GBT 440) is a Haemoglobin S (HbS) Polymerization Inhibitor
Hemoglobin is the special protein that carries oxygen in red blood cells and gives blood red color. Moreover, globin and heme composes hemoglobin. Thereinto, the globin portion is a tetramer consisting…