![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/07/ON1231320-is-a-Highly-Specific-PLK2-Inhibitor-2021-07-13.jpg)
Polo-like kinases (PLKs) have numerous roles in both mitosis and meiosis, including functions related to chromosome segregation, cohesin removal, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/SBP-7455-is-an-Orally-Active-Dual-ULK1-ULK2-Autophagy-Inhibitor-2020-01-23.jpg)
Autophagy is a multi-step pathway initiated through the ULK preinitiation complex, which consists of unc-51-like autophagy activating kinase 1 (ULK1)…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/BETd-246-is-a-PROTAC-Based-BET-BRD-Degrader-2020-11-12.jpg)
In previous blogs, we have introduced a lot of PROTAC based degraders, including TD-428, HJB97, A1874, etc. Coincidentally most of…