Plecanatide is an Orally Active Guanylate Cyclase-C (GC-C) Receptor Agonist
Guanylyl cyclase-C (GC-C) is a transmembrane receptor for bacterial heat-stable enterotoxin and the mammalian peptides guanylin and uroguanylin. Guanylyl cyclase-C mediates intestinal ion secretion and affects intestinal cell growth via…