![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/GS143-is-a-Selective-IκBα-Ubiquitination-Inhibitor-2020-09-02.jpg)
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. Firstly, when GS143…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/11/BRD5529-is-a-Selective-CARD9–TRIM62-PPI-Inhibitor-2019-11-18.jpg)
The allele family CARD9 variant relates to increased or protected risk of inflammatory bowel disease (IBD). Moreover, the susceptible variant…