Tuberculosis, one of the oldest known human diseases, is a potentially serious infectious disease that mainly affects the lungs. It…
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. In addition,…
CCR3 is a chemokine receptor. CCR3 is abundant in eosinophils, mast cells, basophils, and human Th2-like T lymphocyte subsets β…
Zatebradine (UL-FS-49) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC50 of 1.96 µM. Zatebradine reduces…
Darapladib (SB-480848) is a potent, selective, freely reversible, non-covalently bound, orally active inhibitor of Lp-PLA2 with an IC50 of 0.25 nM, and…