IL-6 (Interleukin 6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. Besides, IL-6 signals…
JNJ-61803534 is a potent and orally active RORγt inverse agonist. JNJ-61803534 exhibits anti-inflammatory activity. It inhibits IL-17A production in human…
mAChRs (muscarinic acetylcholine receptors) are G-protein-coupled receptors and exist in five subtypes. The M1, M3 and M5 receptors are excitatory…
MPDE5 is an enzyme derived from phosphodiesterases, present in various tissues, including rods and cones of the retina, and belongs…
Omaveloxolone (RTA 408) is an agent for Friedreich’s Ataxia. And it acts through a combination of activation of the antioxidative…