![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/05/GLPG2534-is-an-Orally-Active-IRAK4-Inhibitor-for-Inflammatory-Skin-Diseases-Research-20230602.jpg)
Kinases typically integrate signaling events down-stream of multiple cytokine receptors. Hence, kinase inhibitors distinguish themselves from cytokine-targeted biologicals by their…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/06/SB-435495-is-an-Orally-Active-Lp-PLA2-Inhibitor-for-Diabetes-Research-20230601.jpg)
Lp-PLA2 (Lipoprotein-associated phospholipase A2) is a calcium-independent serine lipase of 50-kDa that hydrolyzes the acetyl group at the sn-2 position…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/05/Cyclocurcumin-is-a-Potent-p38α-Inhibitor-for-Rheumatoid-Arthritis-Research-20230531.jpg)
p38 mitogen-activated protein kinase (MAPK) plays a key role in cellular response, proliferation, survival, cell cycle and cancer migration. Moreover, the…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/05/Efipladib-is-an-Orally-Active-cPLA2α-Inhibitor-for-Inflammation-Research-2023-0530.jpg)
cPLA2α is an intracellular calcium dependent PLA2. It is expressed in a wide variety of tissues and cells. Firstly, cPLA2α…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/05/Fezolinetant-is-an-NK3R-Antagonist-for-Menopausal-Hot-Flushes-Research-20230529.jpg)
Neurokinin 3 receptor (NK3R) is the most selective of the tachykinin receptors, with highly preferential binding and activation by its…