Calcium-activated chloride channels (CaCCs) are always expressed in epithelial and nonepithelial cells. They are involved in epithelial fluid secretion, sensory…
Atopic dermatitis is a chronically relapsing inflammatory skin disease. The characteristics of atopic dermatitis are eczema and even pruritus. The…
Perindoprilat (S 9780) is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 value ranging from 1.5 nM. Besides, Perindoprilat shows an affinity for…
Phosphodiesterases (PDEs) are enzymes that catalyze the hydrolysis of the 3′ cyclic phosphate bond of cyclic nucleotides. PDEs can break…
Cyclooxygenase (COX), also called prostaglandin endoperoxide synthase, is an oxidoreductase enzyme, including two isoforms: COX-I and COX-II. It acts in…