I-287 is an Orally Active PAR2 Inhibitor for Inflammation Research
Effect of I-287 on intracellular signaling pathways induced by the two human PAR2 agonists, Trypsin, and SLIGKV-NH2.
Effect of I-287 on intracellular signaling pathways induced by the two human PAR2 agonists, Trypsin, and SLIGKV-NH2.
B-cell-activating factor (BAFF) is a member of the tumour-necrosis factor (TNF) family. BAFF is a trimeric membrane-bound or soluble factor. BAFF binds to three receptors: BCMA (B-cell maturation antigen), TACI…
CXCR3, which belongs to the transmembrane G protein-coupled receptor (GPCR) superfamily, is an inflammatory chemokine receptor. This chemokine receptor can regulate immune cell behavior and promote chemotaxis, cell adhesion as…