![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/GKA50-is-a-Potent-Glucokinase-Activator-2021-05-06.jpg)
Glucokinase (GK) is the rate-limiting enzyme of hepatic glucose metabolism and acts as a sensor for glucose-stimulated insulin release in β-cells.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/AMG-837-is-an-Orally-Active-and-Partial-Agonist-of-GPR40-FFA1-2021-04-20.jpg)
Free fatty acid receptor 1 (FFA1), also known as GPR40, is a class of G protein-coupled receptors. FFA1 strongly expresses…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/BC1618-an-Orally-Active-Fbxo48-Inhibitor-Stimulates-Ampk-Dependent-Signaling-2021-04-10.jpg)
The adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a central regulator of metabolic pathways. Increasing AMPK activity is an attractive…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/BRD3308-a-Highly-Selective-HDAC3-Inhibitor-Activates-HIV-1-Transcription-and-Disrupts-HIV-1-Latency-2020-05-02.jpg){kind=spacer}
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl-lysine amino acid on a histone.…