![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/01/KN-62-is-a-Selective-CaMKII-Inhibitor-2022-01-26.jpg)
CaMKs are activated by the increase of intracellular calcium (Ca2+) and calmodulin concentrations. CaM is a Ca2+ effector protein, including…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/08/CLP-3094-is-a-BF3-Directed-Androgen-Receptor-Inhibitor-and-GPR142-Antagonist-2021-08-17.jpg)
The androgen receptor (AR) plays a pivotal role in the development of the prostate gland. It also has relations with…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/GKA50-is-a-Potent-Glucokinase-Activator-2021-05-06.jpg)
Glucokinase (GK) is the rate-limiting enzyme of hepatic glucose metabolism and acts as a sensor for glucose-stimulated insulin release in β-cells.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/AMG-837-is-an-Orally-Active-and-Partial-Agonist-of-GPR40-FFA1-2021-04-20.jpg)
Free fatty acid receptor 1 (FFA1), also known as GPR40, is a class of G protein-coupled receptors. FFA1 strongly expresses…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/BC1618-an-Orally-Active-Fbxo48-Inhibitor-Stimulates-Ampk-Dependent-Signaling-2021-04-10.jpg)
The adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a central regulator of metabolic pathways. Increasing AMPK activity is an attractive…